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The emergence of the BRICS and their development constitutes one of the central facts for analyzing the profound transformation in the map of world power, observing some of the main trends of the contemporary historical-spatial transition of the world system and delving into the geopolitical and geo-economic dimensions of this transition. The central problem of this research is to investigate the significance of the BRICS as the rise and insubordination of the semi-periphery, led by middle powers of continental scale in global articulation, and from there to examine its enlargement in September 2023 (to take effect in January 2024) as an extension of this process to other territories of the Global South, which is related to a set of structural trends in the transition of the world system.